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Combinatorial Chemistry: Synthesis and Application |  | Creators: Stephen R. Wilson, Anthony W. Czarnik
Publisher: Wiley-Interscience
Category: Book
List Price: $149.95
Buy New: $2.99
as of 7/31/2010 03:00 CDT details
You Save: $146.96 (98%)
New (22) Used (12) from $2.99
Seller: ibershop
Rating:  3 reviews
Media: Hardcover
Edition: 1
Pages: 288
Number Of Items: 1
Shipping Weight (lbs): 1.3
Dimensions (in): 9.5 x 6.4 x 0.8
ISBN: 047112687X
Dewey Decimal Number: 615.19
EAN: 9780471126874
Availability: Usually ships in 1-2 business days
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| Editorial Reviews:
Product Description
The new time-saving revolution in drug discovery.
Combinatorial chemistry, a method for synthesizing millions of chemical compounds much faster than usual, is becoming one of the most useful technical tools available to chemists and researchers working today. Using current advances in computer and laboratory techniques, combinatorial chemistry has freed professionals from the drudgery of piecemeal experimental work and opened new creative possibilities for experimentation.
Combinatorial Chemistry: Synthesis and Application details critical aspects of the technique, featuring the work of some of the world's leading chemists, many of whom played a key role in its development. Including examples of both solution-phase and solid-phase approaches as well as the full complement of organic chemistry technologies currently available, the book describes:
* Concepts and terms of combinatorial chemistry
* Polymer-supported synthesis of organic compounds
* Macro beads as microreactors
* Solid-phase methods in combinatorial chemistry
* Encoded combinatorial libraries, including Rf-encoding of synthesis beads
* Strategies for combinatorial libraries of oligosaccharides
* Combinatorial libraries of peptides, proteins, and antibodies using biological systems.
While combinatorial chemistry originated in peptide chemistry, this volume has deliberately focused on nonpeptide organic applications, illustrating the technique's wide uses. Combinatorial Chemistry introduces organic, medicinal, and pharmaceutical chemists as well as biochemists to this exciting, cost-effective, and practical technique, which has unlocked creative potential for the next millennium.
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| Customer Reviews:
 An excellent book July 30, 1999
0 out of 1 found this review helpful
This was easy to read and really focussed on the organic chemistry aspects of combinatorial chemistry. I liked it MUCH better than the previous reviewer.
 A messy affair... May 24, 1999
2 out of 2 found this review helpful
This book explores the subject of combinatorial chemistry especially on organic applications. The book is devided in 12 chapters written by a total of 26 prominent chemists but this makes the book a messy affair because there is a lot of repetitions of definitions etc. All in all, I would not recommend this book neither for newcomers nor skilled chemists.
For the experienced reader May 4, 2000
0 out of 1 found this review helpful
The book is treating a new subject with few firmly established definitions and methods. The authors, who are describing their own work only, therefore become to subjective about the success of their method. This does not belong in a textbook, and the book should therefore considered merely as a compilation of personal comments/reviews. There are also too many repetitions of e.g. definitions, which sometimes are differing from chapter to chapter. In my opinion the book is more suited for readers who have some knowledge of the field beforehand, however, in that case the book is an excellent compilation of different methods and ideas.
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